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1

Pathogenesis and Treatment of Sickle Cell Disease

Epstein, Franklin H., Bunn, H. Franklin

Journal:

Boston Medical and Surgical Journal

Year:

1997

Language:

english

File:

PDF, 332 KB

english, 1997

2

Analysis of Orthologous Gene Expression between Human Pulmonary Adenocarcinoma and a Carcinogen-Induced Murine Model

Robert S. Stearman, Lori Dwyer-Nield, Laura Zerbe, Stacy A. Blaine, Zeng Chan, Paul A. Bunn Jr., Gary L. Johnson, Fred R. Hirsch, Daniel T. Merrick, Wilbur A. Franklin, Anna E. Baron, Robert L. Keith,

Journal:

The American Journal of Pathology

Year:

2005

Language:

english

File:

PDF, 1.59 MB

english, 2005

3

Molecular Predictors of Outcome With Gefitinib in a Phase III Placebo-Controlled Study in Advanced Non-Small-Cell Lung Cancer

Hirsch, F. R., Varella-Garcia, M., Bunn, P. A., Franklin, W. A., Dziadziuszko, R., Thatcher, N., Chang, A., Parikh, P., Pereira, J. R., Ciuleanu, T., von Pawel, J., Watkins, C., Flannery, A., Ellison,

Journal:

Journal of Clinical Oncology

Year:

2006

Language:

english

File:

PDF, 191 KB

english, 2006

4

Asymmetrical hemoglobin hybrids. Approach to the study of subunit interactions

Bunn, H. Franklin, McDonough, Margaret

Journal:

Year:

1974

Language:

english

File:

PDF, 2.43 MB

english, 1974

5

Causes and implications of the correlation between forest productivity and tree mortality rates

Stephenson, Nathan L., van Mantgem, Phillip J., Bunn, Andrew G., Bruner, Howard, Harmon, Mark E., O'Connell, Kari B., Urban, Dean L., Franklin, Jerry F.

Journal:

Ecological Monographs

Year:

2011

Language:

english

File:

PDF, 825 KB

english, 2011

6

Treating sickle cell disease by targeting HbS polymerization

Eaton, William A., Bunn, H. Franklin

Journal:

Year:

2017

Language:

english

File:

PDF, 524 KB

english, 2017

7

The use of hemoglobin as a blood substitute

H. Franklin Bunn

Journal:

American Journal of Hematology

Year:

1993

Language:

english

File:

PDF, 567 KB

english, 1993

8

Influence of inflammatory polyarthritis on cancer incidence and survival: Results from a community-based prospective study

Jarrod Franklin, Mark Lunt, Diane Bunn, Deborah Symmons, Alan Silman

Journal:

Arthritis & Rheumatism

Year:

2007

Language:

english

File:

PDF, 111 KB

english, 2007

9

Epidermal growth factor receptor immunohistochemistry : Comparison of antibodies and cutoff points to predict benefit from gefitinib in a phase 3 placebo-controlled study in advanced nonsmall-cell lung cancer

Fred R. Hirsch, Rafal Dziadziuszko, Nick Thatcher, Helen Mann, Claire Watkins, Dinah V. Parums, Georgina Speake, Brian Holloway, Paul A. Bunn Jr, Wilbur A. Franklin

Journal:

Year:

2008

Language:

english

File:

PDF, 151 KB

english, 2008

10

New anti-lung-cancer antibody cluster 12 reacts with human folate receptors present on adenocarcinoma

Wilbur A. Franklin, Mauricio Waintrub, Dean Edwards, Kurt Christensen, Paul Prendegrast, Jan Woods, Paul A. Bunn, S. Fred Kolhouse

Journal:

International Journal of Cancer

Year:

1994

Language:

english

File:

PDF, 842 KB

english, 1994

11

C225 anti-epidermal growth factor receptor (EGFR) monoclonal antibody sensitizes human non-small cell lung cancer to both radiation and chemotherapy cytotoxicity in-vitro and in-vivo

B. Helfrich, D. Raben, D. Chan, L. Garcia, T. Shogun, W. Zundel, F. Hirsch, W. Franklin, P. Bunn

Journal:

International Journal of Radiation Oncology*Biology*Physics

Year:

2001

Language:

english

File:

PDF, 16 KB

english, 2001

12

Dissociation of Haemoglobin Chesapeake into Subunits

BUNN, H. FRANKLIN

Journal:

Year:

1970

File:

PDF, 216 KB

1970

13

Competition of normal β chains and sickle haemoglobin β chains for α chains as a post-translational control mechanism

SHAEFFER, JOSEPH R., KINGSTON, ROBERT E., MCDONALD, MELISENDA J., BUNN, H. FRANKLIN

Journal:

Year:

1978

File:

PDF, 375 KB

1978

14

Electrostatic interactions in the assembly of haemoglobin

Bunn, H. Franklin, McDonald, Melisenda J.

Journal:

Year:

1983

File:

PDF, 365 KB

1983

15

Erythropoietin gene regulation depends on heme-dependent oxygen sensing and assembly of interacting transcription factors

Huang, L Eric, Ho, Vincent, Arany, Zoltan, Krainc, Dimitri, Galson, Deborah, Tendler, Drory, Livingston, David M, Bunn, H Franklin

Journal:

Kidney International

Year:

1997

Language:

english

File:

PDF, 816 KB

english, 1997

16

Evaluation of HER-2/neu gene amplification and protein expression in non-small cell lung carcinomas

Hirsch, F R, Varella-Garcia, M, Franklin, W A, Veve, R, Chen, L, Helfrich, B, Zeng, C, Baron, A, Bunn, P A

Journal:

British Journal of Cancer

Year:

2002

Language:

english

File:

PDF, 529 KB

english, 2002

17

Oncogene status predicts patterns of metastatic spread in treatment-naive nonsmall cell lung cancer

Robert C. Doebele, Xian Lu, Christopher Sumey, DeLee A. Maxson, Andrew J. Weickhardt, Ana B. Oton, Paul A. Bunn Jr, Anna E. Barón, Wilbur A. Franklin, Dara L. Aisner, Marileila Varella-Garcia, D. Ross

Journal:

Year:

2012

Language:

english

File:

PDF, 772 KB

english, 2012

18

Regulation of the erythropoietin gene

Kerry L. Blanchard, Joachim Fandrey, Mark A. Goldberg, Dr. H. Franklin Bunn

Journal:

Year:

1993

Language:

english

File:

PDF, 528 KB

english, 1993

19

Promoter characterization and transcriptional regulation of Ncb5or, a novel reductase necessary for pancreatic β-cell maintenance

Kevin Larade, H. Franklin Bunn

Journal:

Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression

Year:

2006

Language:

english

File:

PDF, 491 KB

english, 2006

20

Epidermal growth factor receptor expression, signal pathway, and inhibitors in non–small cell lung cancer

Paul A. Bunn Jr, Wilbur Franklin

Journal:

Seminars in Oncology

Year:

2002

Language:

english

File:

PDF, 571 KB

english, 2002

21

Epidermal growth factor receptor family in lung cancer and premalignancy

Wilbur A Franklin, Robert Veve, Fred R Hirsch, Barbara A Helfrich, Paul A Bunn Jr

Journal:

Seminars in Oncology

Year:

2002

Language:

english

File:

PDF, 308 KB

english, 2002

22

HER2/neu expression in malignant lung tumors

Fred R Hirsch, Wilbur A Franklin, Robert Veve, Marileila Varella-Garcia, Paul A Bunn Jr

Journal:

Seminars in Oncology

Year:

2002

Language:

english

File:

PDF, 121 KB

english, 2002

23

Expression of target molecules in lung cancer: Challenge for a new treatment paradigm

Fred R Hirsch, Wilbur A Franklin, Paul A Bunn Jr

Journal:

Seminars in Oncology

Year:

2002

Language:

english

File:

PDF, 87 KB

english, 2002

24

A Hypothesis for the Increased Oxygen Affinity in Haemoglobin Malmö

Solomon J. Zak, Gary R. Geller, William Rrivit, David Tukey, Bernadine Brimhall, Richard T. Jones, H. Franklin Bunn, Michael McCormack

Journal:

British Journal of Haematology

Year:

1976

Language:

english

File:

PDF, 247 KB

english, 1976

25

THE USE OF GEL ELECTROFOCUSING IN THE STUDY OF HUMAN HEMOGLOBINS

H. Franklin Bunn

Journal:

Annals of the New York Academy of Sciences

Year:

1973

Language:

english

File:

PDF, 1.80 MB

english, 1973

26

THE ROLE OF 2,3-DIPHOSPHOGLYCERATE IN MEDIATING HEMOGLOBIN FUNCTION OF MAMMALIAN RED CELLS

H. Franklin Bunn, Ulysses S. Seal, Alan F. Scott

Journal:

Annals of the New York Academy of Sciences

Year:

1974

Language:

english

File:

PDF, 591 KB

english, 1974

27

Structural Analysis of the Minor Human Hemoglobin Components: Hb AIa1, Hb AIa2 and Hb AIb

Laura M. GARRICK, Melisenda J. McDONALD, Robert SHAPIRO, Margaret BLEICHMAN, Michael McMANUS, H. Franklin BUNN

Journal:

Year:

1980

Language:

english

File:

PDF, 564 KB

english, 1980

28

Effects of Transition Metals on the Expression of the Erythropoietin Gene: Further Evidence That the Oxygen Sensor Is a Heme Protein

Vincent T. Ho, H.Franklin Bunn

Journal:

Biochemical and Biophysical Research Communications

Year:

1996

Language:

english

File:

PDF, 2.53 MB

english, 1996

29

Treatment of iron overload in adults with continuous parenteral desferrioxamine

Barry Cooper, H. Franklin Bunn, Richard D. Propper, David G. Nathan, David S. Rosenthal, William C. Moloney

Journal:

The American Journal of Medicine

Year:

1977

Language:

english

File:

PDF, 2.45 MB

english, 1977

30

Nonenzymatic glycosylation of protein: Relevance to diabetes

H.Franklin Bunn

Journal:

The American Journal of Medicine

Year:

1981

Language:

english

File:

PDF, 727 KB

english, 1981

31

The separation of human and animal hemoglobins by isoelectric focusing in polyacrylamide gel

James W. Drysdale, Piergiorgio Righetti, H.Franklin Bunn

Journal:

Biochimica et Biophysica Acta (BBA) - Protein Structure

Year:

1971

Language:

english

File:

PDF, 1.21 MB

english, 1971

32

Oxygen sensing and signaling: impact on the regulation of physiologically important genes

Hao Zhu, H.Franklin Bunn

Journal:

Respiration Physiology

Year:

1999

Language:

english

File:

PDF, 317 KB

english, 1999

33

Erythropoietin induction in Hep3B cells is not affected by inhibition of heme biosynthesis

Hyogo Horiguchi, H. Franklin Bunn

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Year:

2000

Language:

english

File:

PDF, 397 KB

english, 2000

34

EGFR regulation by microRNA in lung cancer: correlation with clinical response and survival to gefitinib and EGFR expression in cell lines

Weiss, G. J., Bemis, L. T., Nakajima, E., Sugita, M., Birks, D. K., Robinson, W. A., Varella-Garcia, M., Bunn, P. A., Haney, J., Helfrich, B. A., Kato, H., Hirsch, F. R., Franklin, W. A.

Journal:

Annals of Oncology

Year:

2008

Language:

english

File:

PDF, 276 KB

english, 2008

35

Combination of EGFR gene copy number and protein expression predicts outcome for advanced non-small-cell lung cancer patients treated with gefitinib

Hirsch, F., Varella-Garcia, M, Cappuzzo, F, McCoy, J, Bemis, L, Xavier, A., Dziadziuszko, R, Gumerlock, P, Chansky, K, West, H, Gazdar, A., Crino, L, Gandara, D., Franklin, W., Bunn, P.

Journal:

Annals of Oncology

Year:

2006

Language:

english

File:

PDF, 127 KB

english, 2006

36

Further identification of the nature and linkage of the carbohydrate in hemoglobin A1c

H.Franklin Bunn, David N. Haney, Kenneth H. Gabbay, Paul M. Gallop

Journal:

Biochemical and Biophysical Research Communications

Year:

1975

Language:

english

File:

PDF, 419 KB

english, 1975

37

Role of nonenzymatic glycosylation in experimental cataract formation

Shyh-Horng Chiou, Leo T. Chylack Jr., H.Franklin Bunn, Jin H. Kinoshita

Journal:

Biochemical and Biophysical Research Communications

Year:

1980

Language:

english

File:

PDF, 391 KB

english, 1980

38

Evaluation of HER2/neu expression in lung tumors by immunohistochemistry and fluorescence in situ hybridization (FISH)

Hirsch, F.R, Veve, R, Varella-Garcia, L, Bunn, P.A, Franklin, W.A

Journal:

Year:

2000

Language:

english

File:

PDF, 235 KB

english, 2000

39

Preliminary results from a phase II trial evaluating 13 cis-retinoic acid with or without alpha tocopherol or observation in patients at high risk for lung cancer

Kelly, K, Dempsey, E, Kennedy, T, Miller, Y, Franklin, W, Prindiville, S, Holte, J, Bunn, P.A

Journal:

Year:

2000

Language:

english

File:

PDF, 108 KB

english, 2000

40

A randomized study of fluorescence bronchoscopy versus white-light bronchoscopy for early detection of lung cancer in high risk patients

Kennedy, T.C, Hirsch, F.R, Miller, Y.E, Prindiville, S, Murphy, J.R, Dempsey, E, Proudfoot, S, Bunn, P.A, Franklin, W.A

Journal:

Year:

2000

Language:

english

File:

PDF, 223 KB

english, 2000

41

What is the role of HER-2/neu and trastuzumab (HERCEPTIN®) in lung cancer?

Hirsch, Fred R., Franklin, Wilbur A., Bunn, Paul A.

Journal:

Year:

2002

Language:

english

File:

PDF, 54 KB

english, 2002

42

IV international conference on prevention and early detection of lung cancer, Reykjavik, Iceland, August 9–12, 2001

Hirsch, Fred R., Bunn, P.A., Dmitrovsky, E., Field, J.K., Franklin, W.A., Greenberg, R.E., Hansen, H.H., Henschke, C.I., Rigas, James R., Smith, R.A., Toennesen, P., Mulshine, J.L.

Journal:

Year:

2002

Language:

english

File:

PDF, 231 KB

english, 2002

43

O-131 High prevalence of endobronchial malignancy in high-risk patients who have moderate dysplasia in sputum

Kennedy, Timothy C., Franklin, Wilbur A., Keith, Robert L., Hirsch, Fred R., Merrick, Thomas A., Shroyer, Kenneth, Petty, Thomas L., Byers, Tim, Bunn, Paul A., Miller, York E.

Journal:

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

44

O-76 Oligonucleotide microarray gene expression profiles of lung cancer cell lines sensitive and resistant to ZD-1839

Franklin, Wilbur A., Helfrich, Barbara A., Sugita, Michio, Lapadat, Razvan, Hirsch, Fred R., Bunn, Paul A.

Journal:

Year:

2003

Language:

english

File:

PDF, 185 KB

english, 2003

45

O-296 Aberrant DNA methylation and sputum atypia predict lung cancer — Preliminary report from the University of Colorado SPORE high risk cohort study

Hirsch, Fred R., Belinski, Steven A., Kennedy, Timothy C., Miller, York E., Franklin, Wilbur A., Wolf, Holly J., Bunn, Paul A., Byers, Tim

Journal:

Year:

2003

Language:

english

File:

PDF, 285 KB

english, 2003

46

P-273 The role of Ki67, p53, EGFR, HER2 and CD31 as possible predictive biomarkers for development of lung cancer in a high-risk population

Winterhalder, Ralph C., Kotantoulas, Georgia, Miller, York E., Kittelson, John, Keith, Robert L., Ingeberg, Steen, Bunn, Paul A., Franklin, Wilbur A., Hirsch, Fred R.

Journal:

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

47

P-272 Angiogenic squamous dysplasia (ASD): A biomarker highly associated with squamous cell lung carcinoma

Keith, Robert L., Miller, York E., Kennedy, Timothy C., Hirsch, Fred R., Kittelson, John, Bunn, Paul A., Kelly, Karen, Franklin, Wilbur A.

Journal:

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

48

P-277 A histological model to predict airway response to promising chemoprevention agents in phase II lung cancer prevention trials

Kelly, Karen, Kittelson, John, Lambert-Kerzner, Anne, Hirsch, Fred R., Franklin, Wilbur, Keith, Robert L., Kennedy, Timothy C., Miller, York E., Bunn, Paul A.

Journal:

Year:

2003

Language:

english

File:

PDF, 177 KB

english, 2003

49

O-107 FISH and Immunohistochemistry (IHC) can be used to selectNSCLC patients, who will not benefit from gefitinib treatment

Hirsch, F., McCoy, J., Cappuzzo, F., Howard Jack, W., Gumerlock, P., Crino, L., Franklin, W., Gandara, D., Varella-Garcia, M., Bunn, P.

Journal:

Year:

2005

Language:

english

File:

PDF, 148 KB

english, 2005

50

O-191 HER1-HER2-HER3 gene amplification and akt activation inpatients with advanced non-small cell lung cancer (NSCLC) treated with gefitinib

Cappuzzo, F., Varella-Garcia, M., Toschi, L., Domenichini, I., Ceresoli, G., Gregorc, V., Franklin, W., Crinò, L., Bunn, P., Hirsch, F.

Journal:

Year:

2005

Language:

english

File:

PDF, 283 KB

english, 2005

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